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KMID : 0358219940210020157
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Korean Journal of Fertility and Sterility
1994 Volume.21 No. 2 p.157 ~ p.164
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Antisperm Antibodies by the Immunobead Test and Pregnancy after Vasovasostomy
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Abstract
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With the indirect immunobead antisperm antibody test (IBT) a prospective study was conducted to evaluate the immune status of 38 men before vasovasostomy. The pregnancy and postoperative semen analysis were evaluated. The results were compared
between
pregnant (n=14) and non-pregnant (n=24) group.
The postoperative sperm motility was inversely correlated with the titer of the preoperative and postoperative IgG (p<0.01). The preoperative and postoperative titer of IgG were significantly higher than the titer of IgA or IgM (p<0.05). The mean
percentage of the positive IBT (20 per cent binding or more) of the pregnant group was significantly lower than non-pregnant group in the preoprative and postoperative IgG (p<0.05). Immunobead binding restricted to the head and tail of a sperm in
IgG
was predominant and significantly lower in the pregnant group (p<0.05).
In conclusion, IgG especially immunobead binding to the head and tail can be used as a sensitive screening assay for antisperm antibodies after vasovasostomy.
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KEYWORD
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